KDM4D crosstalks with PARP1 and RNA at DNA DSBs
نویسندگان
چکیده
منابع مشابه
Histone methyltransferase Dot1 and Rad9 inhibit single-stranded DNA accumulation at DSBs and uncapped telomeres
Cells respond to DNA double-strand breaks (DSBs) and uncapped telomeres by recruiting checkpoint and repair factors to the site of lesions. Single-stranded DNA (ssDNA) is an important intermediate in the repair of DSBs and is produced also at uncapped telomeres. Here, we provide evidence that binding of the checkpoint protein Rad9, through its Tudor domain, to methylated histone H3-K79 inhibits...
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ژورنال
عنوان ژورنال: Cell Cycle
سال: 2015
ISSN: 1538-4101,1551-4005
DOI: 10.1080/15384101.2015.1032648